About
Roasted coffee is produced by heat-treating green coffee beans (Coffea arabica or Coffea canephora/robusta) at high temperatures (typically 180–240 °C), triggering Maillard reactions that develop the characteristic aroma, flavour, and brown pigmentation. It is consumed globally as a brewed beverage and is widely used as a flavouring agent in foods and beverages.
Safety summary
IARC (2016, Monographs Vol. 116) re-classified drinking coffee as Group 3 (not classifiable as carcinogenic to humans) after reviewing over 1,000 studies, and found probable protective associations with liver and uterine endometrial cancer. However, acrylamide—an IARC Group 2A probable carcinogen formed during the Maillard roasting reaction—is present at trace levels; EFSA monitored an average of 221 µg/kg acrylamide in roasted coffee. Caffeine content warrants caution in pregnant women (EFSA recommends ≤200 mg/day total caffeine) and should be avoided in infants and young children; very hot coffee consumption (>65 °C) is classified as IARC Group 2A due to oesophageal cancer risk from thermal injury.
Regulatory landscape
| Jurisdiction | Status | Note |
|---|---|---|
| EFSA (European Food Safety Authority) (European Union) | Approved | EFSA caffeine safety opinion (2015): habitual caffeine intake up to 400 mg/day is safe for non-pregnant adults; single doses up to 200 mg (~3 mg/kg bw for a 70-kg adult) do not raise safety concerns. For pregnant women, total caffeine from all sources should not exceed 200 mg/day. Limit applies to caffeine as a constituent of coffee, not roasted coffee as a whole food.source |
| FDA (Food and Drug Administration) (United States) | Approved | Coffee was included in FDA's original partial list of GRAS substances submitted during congressional hearings on the Food Additives Amendment (21 CFR); recognised as generally safe for use as a food and beverage ingredient. No specific maximum intake established for the whole ingredient.source |
Who should approach with care
Research citations
- 1EFSA. Acrylamide in food — EFSA topic page. efsa.europa.eu
- 2FDA. Enhancing the Regulatory Decision-Making Approval Process for Direct Food Ingredient Technologies — FDA GRAS History (NCBI Bookshelf NBK224037). ncbi.nlm.nih.gov
- 3PubMed. Production and Inhibition of Acrylamide during Coffee Processing: A Literature Review, 2023. pmc.ncbi.nlm.nih.gov
- 4PubMed. Comparison of acrylamide and furan concentrations, antioxidant activities, and volatile profiles in cold or hot brew coffees, 2020. pmc.ncbi.nlm.nih.gov
- 5IARC. Carcinogenicity of drinking coffee, maté, and very hot beverages — IARC Monographs Volume 116, 2016. iarc.who.int
- 6EFSA. Scientific Opinion on the safety of caffeine (EFSA NDA Panel, 2015), 2015. efsa.europa.eu
