About
Flaxseeds are the small oil-rich seeds of Linum usitatissimum, cultivated and consumed for thousands of years as a whole food; they are exceptionally rich in alpha-linolenic acid (omega-3), dietary lignans, protein, and soluble fiber. They are consumed whole, ground, or cold-pressed into oil and are valued for cardiovascular, anti-diabetic, and anti-inflammatory health benefits.
Safety summary
Flaxseeds contain cyanogenic glycosides (chiefly linamarin and linustatin) that hydrolyze to release toxic hydrogen cyanide; the EU has responded by capping HCN content at 150 mg/kg in consumer-retail flaxseeds under Commission Regulation (EU) 2023/915. EFSA estimated that as little as 14.7 g of flaxseed per day could approach the Acute Reference Dose for cyanogenic glycosides, with children and adolescents at elevated risk at the 95th percentile of exposure. Long-term excessive consumption may also carry risks from phytic acid and phytoestrogenic lignans, especially in pregnant women, infants, and persons with thyroid disease.
Regulatory landscape
| Jurisdiction | Status | Note |
|---|---|---|
| EFSA (European Food Safety Authority) (European Union) | Restricted | Commission Regulation (EU) 2023/915 of 25 April 2023 sets maximum HCN contaminant limits in flaxseed: 150 mg/kg for flaxseeds placed on the market for the final consumer; 250 mg/kg for unprocessed whole, crushed, ground, split, or chopped flaxseeds not sold directly to consumers. Based on EFSA CONTAM Panel scientific opinion (EFSA Journal 2019;17(4):5662).source |
| FSSAI (Food Safety and Standards Authority of India) (India) | Approved | Flaxseeds (locally known as alsi/tisi) are a permitted food ingredient under the Food Safety and Standards (Food Products Standards and Food Additives) Regulations, 2011. Naturally occurring toxins including cyanogenic compounds are governed by the FSS (Contaminants, Toxins and Residues) Regulations, 2011. Specific HCN numeric limits for flaxseed are not publicly specified in currently available FSSAI documents; general provisions for naturally occurring toxic substances apply.source |
| FDA (Food and Drug Administration) (United States) | Approved | Flaxseeds are whole food ingredients with a long history of safe use in the US food supply. They are not classified as a food additive and fall outside formal GRAS additive scheduling; no regulatory daily intake ceiling has been established. The FDA does not restrict flaxseed sale or use.source |
Who should approach with care
Research citations
- 1PubMed. Flaxseed in Diet: A Comprehensive Look at Pros and Cons, 2025. pmc.ncbi.nlm.nih.gov
- 2PubMed. Depletion of cyanogenic glycosides in whole flaxseed via Lactobacillaceae fermentation, 2022. pubmed.ncbi.nlm.nih.gov
- 3PubMed. A comprehensive review of flaxseed (Linum usitatissimum L.): health-affecting compounds, mechanism of toxicity, detoxification, anticancer and potential risk, 2022. pubmed.ncbi.nlm.nih.gov
- 4EFSA. Evaluation of the health risks related to the presence of cyanogenic glycosides in foods other than raw apricot kernels, 2019. efsa.europa.eu
- 5PubMed. Ion chromatographic determination of cyanide released from flaxseed under autohydrolysis conditions, 1995. pubmed.ncbi.nlm.nih.gov
